DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment si:dkey-33c12.12 and htra2

DIOPT Version :9

Sequence 1:	NP_001082916.2	Gene:	si:dkey-33c12.12 / 100000024	ZFINID:	ZDB-GENE-081028-30	Length:	214	Species:	Danio rerio
Sequence 2:	XP_031750958.1	Gene:	htra2 / 100492982	XenbaseID:	XB-GENE-6044196	Length:	436	Species:	Xenopus tropicalis

Alignment Length:	202	Identity:	135/202 - (66%)
Similarity:	161/202 - (79%)	Gaps:	2/202 - (0%)

- Green bases have known domain annotations that are detailed below.

Zfish     1 MGSPFSLKNTITSGIISSAQRGSKELGLSNSNMDYIQTDATIDFGNSGGPLINLDGEVIGINTMK 65
            |||||||:|||||||:||.|||..||||:|.:|:||||||.||||||||||:|||||||||||||
Frog   235 MGSPFSLQNTITSGIVSSVQRGGHELGLANRDMEYIQTDAAIDFGNSGGPLVNLDGEVIGINTMK 299

Zfish    66 VTAGISFAIPLGRVRLFLDRSADK--QKSWFGESGWKRRYIGVMMLTLTPSIIEELRMRDPSFPD 128
            |..|||||||..|||.||.....:  |.|..|.|..||||||||||||||.|:.||:.|||||||
Frog   300 VVPGISFAIPSDRVREFLQHGEKRRSQGSLLGSSEVKRRYIGVMMLTLTPKILAELKFRDPSFPD 364

Zfish   129 ISHGVLIHRVIVGSPANRAGMKPGDVIIEINGVKVNTSEEIYNAVRTSESLNVVVRRGADLLMLH 193
            :|||||||:|||||||:.:|::.|||::|||..:..|||:||:||.|...|.::||||::.||:.
Frog   365 VSHGVLIHKVIVGSPAHESGLRAGDVVLEINAKRAMTSEDIYDAVHTHPKLTMIVRRGSESLMVT 429

Zfish   194 MTPESTE 200
            :.||.||
Frog   430 VIPECTE 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
si:dkey-33c12.12	NP_001082916.2	Trypsin_2	<1..61	CDD:290102	48/59 (81%)
si:dkey-33c12.12	NP_001082916.2	PDZ_serine_protease	102..186	CDD:238487	54/83 (65%)
htra2	XP_031750958.1	degP_htrA_DO	125..>431	CDD:273938	131/195 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	225	1.000	Domainoid score	I11048
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	440	1.000	Inparanoid score	I7342
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D210946at7742
OrthoFinder	1	1.000	-	-		FOG0000153
OrthoInspector	1	1.000	-	-		otm36365
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X265
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.060