Protein Alignment AKT3 and akt3a

DIOPT Version :9

• Sequence 1: NP_001357003.1
• Gene: AKT3 / 10000
• HGNCID: 393
• Length: 479
• Species: Homo sapiens
• Sequence 2: NP_001184130.1
• Gene: akt3a / 560549
• ZFINID: ZDB-GENE-050419-180
• Length: 479
• Species: Danio rerio
• Alignment Length: 479
• Identity: 459/479 - (95%)
• Similarity: 472/479 - (98%)
• Gaps: 0/479 - (0%)

Human     1 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQLMKTE 65
            |||||:||||||||||||||||||||||||||||||||||||||.||||||||||||||||||||
Zfish     1 MSDVTVVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDADLPYPLNNFSVAKCQLMKTE 65

Human    66 RPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCSPTSQIDNIGE 130
            ||||||||||||||||||||||||||||||:||.||||.|||:||||||||:.|||||||||:||
Zfish    66 RPKPNTFIIRCLQWTTVIERTFHVDTPEERDEWAEAIQMVADKLQRQEEERIQCSPTSQIDNMGE 130

Human   131 EEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLT 195
            ||||.|.:|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   131 EEMDTSISHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLT 195

Human   196 ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALD 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   196 ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALD 260

Human   261 YLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGR 325
            ||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   261 YLHSAKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGR 325

Human   326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLG 390
            |||||||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||||
Zfish   326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSADAKSLLSGLLIKDPNKRLG 390

Human   391 GGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKYDED 455
            |||||||||||||||:|::|||||||||:|||||||:||||||||||||||||||||||||:|||
Zfish   391 GGPDDAKEIMRHSFFTGIDWQDVYDKKLIPPFKPQVSSETDTRYFDEEFTAQTITITPPEKFDED 455

Human   456 GMDCMDNERRPHFPQFSYSASGRE 479
            ||||||||||||||||||||||||
Zfish   456 GMDCMDNERRPHFPQFSYSASGRE 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AKT3	NP_001357003.1	PH_PKB	4..110	CDD:269947	99/105 (94%)
		STKc_PKB_gamma	132..479	CDD:270745	335/346 (97%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	458..479		20/20 (100%)
akt3a	NP_001184130.1	PH_PKB	4..110	CDD:269947	99/105 (94%)
		PH	6..105	CDD:278594	94/98 (96%)
		STKc_PKB_gamma	132..479	CDD:270745	335/346 (97%)
		S_TKc	148..405	CDD:214567	254/256 (99%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C194331398
Domainoid	1	1.000	518	1.000	Domainoid score	I2518
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55904
Inparanoid	1	1.050	961	1.000	Inparanoid score	I2494
NCBI	1	1.000	-	-
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D164044at7742
OrthoFinder	1	1.000	-	-		FOG0001457
OrthoInspector	1	1.000	-	-		oto44054
orthoMCL	1	0.900	-	-		OOG6_100157
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R469
SonicParanoid	1	1.000	-	-		X913
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	1	1.500	-	-
	15	15.330