The following is the result of an ongoing effort to
compile links to databases that may be of use to people
analyzing RNAi screen hit data. We would like to include
databases of information about Drosophila genes, proteins,
expression, interactions and homology. We have tried to
limit the list to freely available on-line databases. We
welcome suggestions for changes or additions (most recent
update: 11/2008).
ArrayExpress
"is a public repository for transcriptomics data,
which is aimed at storing MIAME- and MINSEQE- compliant
data in accordance with MGED recommendations."
BioGRID
(General Repository for Interaction Datasets) "was
developed to house and distribute collections of protein
and genetic interactions from major model organism
species."
DroID (Drosophila
Interactions Database) "is a comprehensive gene and
protein interactions database designed specifically for
the model organism Drosophila."
DRSC. You're
here. Please go to
the Online
Tools overview page to start a search or learn more
about getting the most from our database.
FLIGHT
facilitates "integration of data from high-throughput
experiments carried out in Drosophila cell
culture."
FlyBase is a
comprehensive, curated database of genetic, genomic,
phenotypic and other information about Drosophila.
FlyMine is an
"integrated database of genomic, expression and
protein data for Drosophila, Anopheles and
C. elegans."
GenomeRNAi
is "a database of phenotypes from systematic RNA
interference (RNAi) screens in cultured Drosophila
cells."
Homophila
at Superfly allows for identification of Drosophila
genes related to human disease genes via comparison of
Drosophila sequence data to human disease gene data in
NCBI's OMIM (Online Mendelian Inheritance in Man)
database.
modENCODE-mine
is "an integrated database of genomic, expression and
protein data for Drosophila and C. elegans" generated
by the modENCODE
project.
NCBI
GEO (Gene Expression Omnibus) is "a gene
expression/molecular abundance repository supporting MIAME
compliant data submissions, and a curated, online resource
for gene expression data browsing, query and
retrieval."
STRING (Search
Tool for the Retrieval of Interacting Genes/Proteins) is
"a database of known and predicted protein-protein
interactions. The interactions include direct (physical)
and indirect (functional) associations; they are derived
from four sources: genomic context, high-throughput
experiments, (conserved) coexpression and previous
knowledge."
