[an error occurred while processing this directive] DRSC: rd.edu"> Drosophila RNAi Screening Center ffort to compile links to databases that may be of use to people analyzing RNAi screen hit data. We would like to include databases of information about Drosophila genes, proteins, expression, interactions and homology. We have tried to limit the list to freely available on-line databases. We welcome suggestions for changes or additions.

External Links, Table View

Name RNAi Screen Hits Expression Interactions Homology
ArrayExpress   Yes    
BioGRID     Yes  
DPiM     Yes  
DroID     Yes Yes
DroPNet     Yes Yes
FLIGHT Yes Yes    
FlyAtlas2   Yes    
FlyBase Yes Yes Yes Yes
FlyMine Yes Yes Yes Yes
GenomeRNAi Yes     Yes
modMine   Yes    
NCBI GEO   Yes    
STRING   Yes Yes Yes
The DRSC database and software tools are described on the Tools Overview page

External Links, List View

ArrayExpress "is a public repository for transcriptomics data, which is aimed at storing MIAME- and MINSEQE- compliant data in accordance with MGED recommendations."

BioGRID (General Repository for Interaction Datasets) "was developed to house and distribute collections of protein and genetic interactions from major model organism species."

DPiM - The Drosophila Protein Interaction Mapping project, which is a collaborative project to establish a complete, unbiased protein interaction map of Drosophila proteome based on the isolation and mass spectrometric analysis of purified protein complexes associated with individually tagged proteins.

DroID (Drosophila Interactions Database) "is a comprehensive gene and protein interactions database designed specifically for the model organism Drosophila."

DroPNet "allows the generation and analysis of protein-protein interaction (PPI) networks" and "will help integrating user experimental data with various available PPI databases."

FLIGHT facilitates "integration of data from high-throughput experiments carried out in Drosophila cell culture."

FlyAtlas2 - Search for Drosophila genes with similar tissue expression pattern based on micro-array data.

FlyBase is a comprehensive, curated database of genetic, genomic, phenotypic and other information about Drosophila.

FlyMine is an "integrated database of genomic, expression and protein data for Drosophila, Anopheles and C. elegans."

GenomeRNAi is "a database of phenotypes from systematic RNA interference (RNAi) screens in cultured Drosophila cells."

modMine is an integrated database of expression, chromatin status and regulatory networks for Drosophila and C. elegans generated by the modENCODE project.

NCBI GEO (Gene Expression Omnibus) is "a gene expression/molecular abundance repository supporting MIAME compliant data submissions, and a curated, online resource for gene expression data browsing, query and retrieval."

STRING (Search Tool for the Retrieval of Interacting Genes/Proteins) is "a database of known and predicted protein-protein interactions. The interactions include direct (physical) and indirect (functional) associations; they are derived from four sources: genomic context, high-throughput experiments, (conserved) coexpression and previous knowledge."

Additional Online Resources of Interest

Bioinformatic Harvester III (beta), which "crawls and crosslinks" data from a variety of "bioinformatic sites."

Interactive Fly, which provides information about Drosophila melanogaster developmental stages, including the Atlas of Drosophila Development.

Resources page at FlyBase.

SIFTED Prediction of TALE DNA binding specificities including potential off-targets